PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: OTI8D3]
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Transient overexpression lysate of ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)
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Specifications
Product Data | |
Clone Name | OTI8D3 |
Applications | ELISA |
Recommended Dilution | ELISA 1:5000-10000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human UCHL1 (NP_004172) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 24.8 kDa |
Gene Name | ubiquitin C-terminal hydrolase L1 |
Database Link | |
Background | The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease. [provided by RefSeq, Sep 2009] |
Synonyms | HEL-117; HEL-S-53; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; SPG79; Uch-L1 |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Parkinson's disease |
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