Shank3 Mouse Monoclonal Antibody [Clone ID: N367/62]

CAT#: 75-344

Shank3 mouse monoclonal antibody, clone N367/62

Product Images

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Shank1, Shank2, Shank3 or untagged Kv2.1 plasmid and probed with N367/62 (left) or N23B/49 (right) TC supe.

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  Adult rat hippocampus immunohistochemistry (with antigen retrieval via sodium citrate pretreatment)

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  Immunoblot against adult rat brain membranes (RBM) and membranes from Shank3 wild-type (WT) and knockout (KO) mice probed with N367/62 (left) or K58/35 (right) TC supe. Mouse brains courtesy of Yuan Mei, Holly Robertson and Guoping Feng (MIT).

Specifications

Product Data

• Clone Name: N367/62
• Applications: IF, IHC, WB
• Recommended Dilution: Immunoblot (IB)
  Immunohistochemistry (IHC)
  Immunocytochemistry (ICC)
• Reactivities: Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (also known as SH3 and multiple ankyrin repeat domains protein 3, Proline-rich synapse-associated protein 2, ProSAP2, PSAP2, SPANK-2 and Kiaa1650, accession number Q9JLU4).
  Mouse: 100% identity (89/89 amino acids identical)
  Human: 97% identity (87/89 amino acids identical)
  ~70% identity with Shank1 and Shank2
• Specificity: Does not cross-react with Shank1 or Shank2
• Formulation: State: Purified
• Conjugation: Unconjugated
• Gene Name: SH3 and multiple ankyrin repeat domains 3
• Database Link:
  Entrez Gene 59312 Rat
  UniProt ID Q9JLU4
• Synonyms: PROSAP2, PSAP2, SPANK-2, SPANK2, KIAA1650
• Note: USERS will cite the UC Davis/NIH NeuroMab Facility in any publication(s) describing the research utilizing the MATERIALS. The suggested acknowledgment statement is as follows:
  "The monoclonal antibody _ was developed by and/or obtained from the UC Davis/NIH NeuroMab Facility, supported by NIH grant U24NS050606 and maintained by the Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, CA 95616."
  Also, please include the complete clone number (e.g., N52A/42) and the Antibody Registry identification number (e.g., RRID:AB_2120479) to avoid ambiguity.
  View Research License Agreement