Cortisol Mouse Monoclonal Antibody [Clone ID: BGN/C53]

CAT#: AM01098PU-N

Cortisol mouse monoclonal antibody, clone BGN/C53, Purified

Specifications

Product Data

• Clone Name: BGN/C53
• Applications: ELISA
• Recommended Dilution: ELISA: 1/500-1/5000.
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Synthetic Corticosterone conjugated to Bovine Serum Albumin.
• Specificity: This antibody recognises the glucocorticoid hormone cortisol, produced in the adrenal cortex and involved in responses to stress.
  Cross reactivity:
  Cortisol: 100%
  Corticosterone: 50%
  Prednisolone: 15%
  11-Desoxycortisol: 0.1%
  Cortisone: < 0.1%
  17-a-OH Progesterone: < 0.1%
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: 1.0 mg/ml
• Background: Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
• Synonyms: Hydrocortisone
• Note: Cortisol CAS Number: 50-23-7