FK506 Mouse Monoclonal Antibody [Clone ID: FK1]

CAT#: AM01339PU-N

FK506 mouse monoclonal antibody, clone FK1, Purified

Datasheet
SDS

USD 475.00

5 Days*

Size
    • 200 ug
Bulk/Customize

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Specifications

Product Data
Clone Name FK1
Applications ELISA
Recommended Dilution ELISA.
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Specificity This antibody clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine.
Formulation TRIS buffered saline, pH 8.0
State: Purified
State: Liquid purified IgM fraction
Preservative: 0.09% Sodium Azide
Concentration 1.0 mg/ml
Background FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Synonyms Tacrolimus, FK-506
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.