Alkaline Phosphatase (ALPL) Mouse Monoclonal Antibody [Clone ID: BGN/03/66KF44]

CAT#: AM05452PU-N

Alkaline Phosphatase (ALPL) mouse monoclonal antibody, clone BGN/03/66KF44, Purified

Specifications

Product Data

• Clone Name: BGN/03/66KF44
• Applications: ELISA, IHC
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 1/25-1/100.
  Recommended Positive Control: Human Liver.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Human bone Alkaline Phosphatase
• Specificity: This antibody is specific for bone and liver Alkaline Phosphatase, a hydrolase enzyme responsible for dephosphorylation of many types of molecules.
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 249 Human
• Background: Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
• Synonyms: AP-TNAP, TNSALP