CD8A Mouse Monoclonal Antibody [Clone ID: 4B11]

CAT#: AM05530SU-T

CD8A mouse monoclonal antibody, clone 4B11


USD 260.00

5 Days*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name 4B11
Applications IHC
Recommended Dilution Immunohistochemistry on Frozen Sections: 1/20-1/40.
Immunohistochemistry on paraffin sections: 1/20-1/40. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. 1mM EDTA pH 8.0 is recommended for this purpose.
Positive Control Tissue: Human Tonsil.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Synthetic peptide derived from CD8 alpha chain sequence.
Specificity This antibody recognizes the Human CD8 cell surface antigen, a 32kD glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells.
Clone 4B11 has been reported as being suitable for use in Western blotting. AM05530SU-N is recommended for this purpose.
Formulation State: Lyophilized Tissue Culture Supernatant containing 0.09% Sodium Azide as preservative.
Reconstitution Method Restore with 1 ml distilled water.
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.