CD51 / ITGAV Rat Monoclonal Antibody [Clone ID: RMV-7]

CAT#: AM05569LE-N

CD51 / ITGAV rat monoclonal antibody, clone RMV-7, Low Endotoxin


USD 745.00

5 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name RMV-7
Applications FC, FN, IP
Recommended Dilution Flow Cytometry: 1/10 - 1/100.
Immunoprecipitation.
Functional Assays.
Reactivities Mouse
Host Rat
Isotype IgG1
Clonality Monoclonal
Immunogen cultured LAK cells from Balb/c mice.
Specificity This antibody recognises CD51. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
Formulation Phosphate buffered saline pH7.4
State: Low Endotoxin
State: Liquid purified IgG
Concentration 1.0mg/ml
Purification Affinity chromatography on Protein G
Background CD51 is a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.
Synonyms Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.