Ly6a Rat Monoclonal Antibody [Clone ID: D7]

CAT#: AM05666FC-N

Ly6a rat monoclonal antibody, clone D7, FITC

Specifications

Product Data

• Clone Name: D7
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/5 - 1/10.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: IL-2-dependent mouse T cell line CTL-L.
• Specificity: This antibody recognises members of the lymphocyte activation protein-6 (Ly6) multigene family. Specifically, it recognises Ly6A.2 and Ly6E.1. Clone D7 has been reported to induce T cell activation.
• Formulation: Borate buffered saline pH8.0 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: FITC
  State: Liquid purified IgG
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5mg/ml
• Conjugation: FITC
• Gene Name: Mus musculus lymphocyte antigen 6 complex, locus A (Ly6a), transcript variant 3
• Database Link:
  Entrez Gene 110454 Mouse
• Background: Ly6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells.
• Synonyms: Lymphocyte antigen 6A-2/6E-1, Ly-6A.2/Ly-6E.1, T-cell-activating protein, TAP, Stem cell antigen 1, SCA-1