IL1 alpha (IL1A) Mouse Monoclonal Antibody

CAT#: AM06011PU-N

IL1 alpha (IL1A) mouse monoclonal antibody, Ascites

Product Images

AM06011PU-N IL1A Antibody staining of Formalin-Fixed Paraffin-Embedded Human Spleen at 1/400 after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 1/400.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant human IL1A / IL1 Alpha
• Specificity: This antibody detects Human Interleukin 1 Alpha (IL1A).
• Formulation: State: Ascites
  State: Unpurified Ascitic fluid
  Preservative: 0.03% Sodium Azide
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 3552 Human
• Background: Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.
• Synonyms: IL-1 alpha, IL1F1, IL1A, Hematopoietin-1