Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: 8A12]
CAT#: AM06775SU-N
Prostate Specific Antigen (KLK3) mouse monoclonal antibody, clone 8A12, Ascites
Specifications
Product Data | |
Clone Name | 8A12 |
Applications | ELISA, FC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500-1/2000. Flow Cytometry: 1/200-1/400. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human KLK3 expressed in E. Coli. |
Specificity | This antibody reacts to KLK3. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. |
Synonyms | Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen |
Reference Data |
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