Cd2 Rat Monoclonal Antibody [Clone ID: 12-15]

CAT#: AM08025LE-N

Cd2 rat monoclonal antibody, clone 12-15, Low Endotoxin


USD 390.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name 12-15
Applications FC, FN, IP
Recommended Dilution Flow Cytometry < / = 1 µg/10e6 cells. (Ref.1-3)
Immunoprecipitation. (Ref.1-2)
Functional Assay:
In vitro Inhibition of CTL-mediated lysis. (Ref.1)
Induction of T cell unresponsiveness in vivo. (Ref.4)
Reactivities Mouse
Host Rat
Isotype IgG1
Clonality Monoclonal
Specificity This antibody is specific to CD2/LFA-2 (Mr 45-58 kDa)
Formulation PBS without preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Background CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. (Ref.1) It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. (Ref.1-3) In the mouse, CD2 is the receptor for CD48. (Ref.4) CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation. (Ref.5-10)
Synonyms SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.