Itgb7 Rat Monoclonal Antibody [Clone ID: DATK32]

CAT#: AM08074LE-N

Itgb7 rat monoclonal antibody, clone DATK32, Low Endotoxin


USD 450.00

3 Days*

Size
    • 500 ug

Product Images

Other products for "Itgb7"

Specifications

Product Data
Clone Name DATK32
Applications FC, FN, IHC
Recommended Dilution Flow Cytometry. (Ref.1-4)
Immunohistochemistry on Frozen Sections. (Ref.3)
Induction of homotypic cellular aggregation. (Ref.1)
Blockade of binding to cell adhesion molecules. (Ref.1)
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref.1)
Specificity This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7).
It recognises a conformational epitope on the heterodimer.
Formulation PBS containing no preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Gene Name Mus musculus integrin beta 7 (Itgb7)
Background The lymphocyte Peyer’s patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)
Synonyms Integrin alpha-4/beta-7, Integrin alpha 4, Integrin beta 7, ITGA4, ITGB7, LPAM1, CD49d, VLA-4
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.