H2-D1 Mouse Monoclonal Antibody [Clone ID: 27-11-13S]

CAT#: AM08082BT-N

H2-D1 mouse monoclonal antibody, clone 27-11-13S, Biotin


USD 360.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name 27-11-13S
Applications FC
Recommended Dilution Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-3)
Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only).
Reactivities Mouse
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen C3H alphaBDF1 splenocytes. (Ref.1)
Specificity This antibody recognizes the alpha 3 domain of H-2Db class I MHC antigen. It cross-reacts with the alpha 3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd.
Reactivity with haplotypes k, f, p, r, and s has not been observed.
Customer feedback: Clone 27-11-13S does not cross-react with human cells.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: Biotin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Conjugation Biotin
Background In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen).
MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant beta 2 Microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.
Synonyms H-2D(B), H2-D1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.