IL5 Rat Monoclonal Antibody [Clone ID: JES1-5A10]
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Specifications
Product Data | |
Clone Name | JES1-5A10 |
Applications | ELISA |
Recommended Dilution | ELISA: Useful useful as a Detection/Capture antibody in a Sandwich ELISA for quantifying human IL-5 protein levels. (Ref.1-5) |
Reactivities | Human |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | COS-expressed recombinant human IL-5. |
Specificity | This antibody is specific to Human Interleukin-5/IL-5. (Ref.1-4) |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Biotin |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and Mouse IL5 have 70% amino acid sequence homology. |
Synonyms | IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF |
Reference Data |
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