TOLLIP Mouse Monoclonal Antibody [Clone ID: k1B17]
Specifications
Product Data | |
Clone Name | k1B17 |
Applications | ELISA, IF, WB |
Recommended Dilution | ELISA. Western blot (1/500-1/1,000). Immunofluorescence. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant human Tollip (61-274 aa) purified from E. coli |
Specificity | The antibody recognizes human TOLLIP. Other species not tested. |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | 1.0 mg/ml |
Purification | Protein-G affinity chromatography |
Database Link | |
Background | Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors(TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. |
Synonyms | Toll-interacting protein |
Reference Data |
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