Gastric Mucin (MUC6) Mouse Monoclonal Antibody [Clone ID: MRQ-20]

CAT#: AM10120SU-N

Gastric Mucin (MUC6) mouse monoclonal antibody, clone MRQ-20, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human gastric mucosa stained with Mucin-6 antibody Cat.-No. AM10120SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of glandular cells.

Specifications

Product Data

• Clone Name: MRQ-20
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Stomach.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Human MUC56 protein.
• Specificity: Recognizes Mucin-6.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Gene Name: Homo sapiens microphthalmia-associated transcription factor (MITF), transcript variant 4
• Database Link:
  Entrez Gene 4588 Human
• Background: Mucin 6 (Muc-6 Glycoprotein). Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6,7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands.
• Synonyms: MUC-6, Gastric mucin-6, MUC6

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Melanogenesis, Melanoma, Pathways in cancer