KLF4 Mouse Monoclonal Antibody [Clone ID: 56CT5.1.6]
Specifications
Product Data | |
Clone Name | 56CT5.1.6 |
Applications | IF, WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/200-1/2000. Immunofluorescence. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | KLF4 recombinant protein. |
Specificity | This antibody is specific to KLF4. |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Kruppel-like factor 4 (gut) |
Database Link | |
Background | Krüppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood. |
Synonyms | EZF, GKL |
Reference Data |
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