CD28 Mouse Monoclonal Antibody [Clone ID: CD28.2]

CAT#: AM12006FC-N

CD28 mouse monoclonal antibody, clone CD28.2, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name CD28.2
Applications FC
Recommended Dilution Flow cytometry analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivities Human, Primate
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA
Specificity The antibody CD28.2 reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
Formulation Phosphate buffered saline (PBS) solution containing 15mM sodium azide
Label: FITC
State: Liquid purified Ig fraction
Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated and adjusted for direct use.
Conjugation FITC
Storage Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD28 molecule (CD28), transcript variant 1
Background CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Synonyms TP44
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.