DEP1 (PTPRJ) (1-444) Mouse Monoclonal Antibody [Clone ID: MEM-CD148/05]

CAT#: AM26703BT-N

DEP1 (PTPRJ) (1-444) mouse monoclonal antibody, clone MEM-CD148/05, Biotin


USD 270.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name MEM-CD148/05
Applications FC
Recommended Dilution Indirect Immunofluorescence analysis by Flow cytometry.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant CD148 (amino acids 1-444)
Formulation Phosphate buffered saline (PBS)
Label: Biotin
State: Liquid purified Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration lot specific
Conjugation Biotin
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name protein tyrosine phosphatase, receptor type J
Background CD148 (also known as HPTP-eta or DEP-1) is a transmembrane protein tyrosin phosphatase containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts, epithelial cells), and signal transduction downstream of T cell receptor, however, it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leucocytes. It can be also used as marker of the most mature human thymocytes, and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast, in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes.
Synonyms DEP1, DEP-1, HPTP eta, R-PTP-eta, Protein-tyrosine phosphatase eta, R-PTP-J
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.