HLA Class II DR Mouse Monoclonal Antibody [Clone ID: L243]

CAT#: AM26708FC-N

HLA Class II DR mouse monoclonal antibody, clone L243, FITC

Product Images

Surface staining of HLA-DR in human peripheral blood with anti-HLA-DR (L243) PerCP-Cy5.5.

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  Surface staining of HLA-DR in human peripheral blood with anti-HLA-DR (L243) APC-Cy7.

Specifications

Product Data

• Clone Name: L243
• Applications: FC
• Recommended Dilution: Flow cytometry analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
  The content of a vial (0.4 ml) is sufficient for 100 tests.
• Reactivities: Canine, Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human B lymphocytes
• Specificity: This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
• Formulation: Phosphate buffered saline (PBS)
  Label: FITC
  State: Liquid Ig fraction
  Preservative: 15 mM sodium azide
• Conjugation: FITC
• Background: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).
• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR