Myeloperoxidase (MPO) Mouse Monoclonal Antibody [Clone ID: MPO421-8B2]

CAT#: AM26774FC-N

Myeloperoxidase (MPO) mouse monoclonal antibody, clone MPO421-8B2, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name MPO421-8B2
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human myeloperoxidase
Specificity This antibody recognizes human myeloperoxidase, a heme protein present in myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.
Formulation Phosphate buffered saline (PBS)
Label: FITC
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative: 15 mM sodium azide
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.
Synonyms MPO
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.