MNK1 (MKNK1) (1-466) Mouse Monoclonal Antibody [Clone ID: 2H8]

CAT#: AM31082PU-N

MNK1 (MKNK1) (1-466) mouse monoclonal antibody, clone 2H8, Purified

Product Images

MKNK1 monoclonal antibody, clone 2H8 Western Blot analysis of MKNK1 expression in HeLa.

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  Western Blot analysis of MKNK1 expression in transfected 293T cell line by MKNK1 monoclonal antibody, clone 2H8.

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  Detection limit for recombinant GST tagged MKNK1 is approximately 3ng/ml as a capture antibody.

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to MKNK1 on HeLa cell. [antibody concentration 10 ug/ml]

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Specifications

Product Data

• Clone Name: 2H8
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MKNK1 (AAH02755, 1 a.a. ~ 466 a.a) full length recombinant protein with GST tag
• Specificity: This antibody reacts to full length MKNK1 / MNK1.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 3
• Database Link:
  Entrez Gene 8569 Human
• Background: MNK1 is an MNK protein kinase that is activated in response to mitogens/insulin by ERK1 and ERK2, or in response to stress by activated p38. MNK1 phosphorylates eIF4E to enhance the translation rates of cap-containing mRNAs.
• Synonyms: MNK1, MAP kinase-interacting serine/threonine-protein kinase 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Insulin signaling pathway, MAPK signaling pathway