MNK1 (MKNK1) Mouse Monoclonal Antibody [Clone ID: 2F12]

CAT#: AM31087PU-N

MNK1 (MKNK1) mouse monoclonal antibody, clone 2F12, Purified

Product Images

MNK1 monoclonal antibody, clone 2F12. Western Blot analysis of MNK1 expression in Raw 264.7. (Isoform : 51.342, 47.402, 39.103 kD)

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to MNK1 on HeLa cell. [antibody concentration 10 ug/ml]

Specifications

Product Data

• Clone Name: 2F12
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: MKNK1 antibody was raised against recombinant protein
• Specificity: This antibody reacts to MKNK1 / MNK1.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: 0.4 mg/ml
• Purification: Protein A chromatography
• Gene Name: Homo sapiens MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 3
• Database Link:
  Entrez Gene 17346 MouseEntrez Gene 8569 Human
• Background: MNK1 is an MNK protein kinase that is activated in response to mitogens/insulin by ERK1 and ERK2, or in response to stress by activated p38. MNK1 phosphorylates eIF4E to enhance the translation rates of cap-containing mRNAs.
• Synonyms: MNK1, MAP kinase-interacting serine/threonine-protein kinase 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Insulin signaling pathway, MAPK signaling pathway