IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: B-G3]

CAT#: AM31171AF-N

IL2 Receptor alpha (IL2RA) mouse monoclonal antibody, clone B-G3, Azide Free


USD 270.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name B-G3
Applications FC
Recommended Dilution Flow Cytometry.
No effect on Mixed Lymphocyte Culture.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen PHA activated T cells
Specificity Recognises both soluble and membrane bound Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein.
Formulation Phosphate-buffered saline.
Sterile-filtered through 0.22 µm.
Carrier and preservative free
State: Azide Free
State: Liquid purfied Ig fraction
Concentration lot specific
Purification Ion exchange chromatography
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens interleukin 2 receptor, alpha (IL2RA), transcript variant 1
Background Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Synonyms Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TAC antigen
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.