ICAM2 Mouse Monoclonal Antibody [Clone ID: B-T1]

CAT#: AM31349FC-N

ICAM2 mouse monoclonal antibody, clone B-T1, FITC

Product Images

A typical staining pattern with the B-T1 monoclonal antibody of lymphocytes.

Specifications

Product Data

• Clone Name: B-T1
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl to label 10⁶ cells in 100 µl of whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: ICAM-2 transfected CHO cells.
• Specificity: Recognises the Intercellular Adhesion Molecule-2 (ICAM-2), a 55-65 kDa protein.
• Formulation: PBS
  Label: FITC
  State: Liquid purified IgG fraction
  Stabilizer: 5% BSA
  Preservative: 0.09% Sodium Azide
  Label: Fluorescein Isothiocyanate Isomer 1
• Purification: Ion Exchange Chromatography
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch
• Gene Name: Homo sapiens intercellular adhesion molecule 2 (ICAM2), transcript variant 5
• Database Link:
  Entrez Gene 3384 Human
• Background: ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
• Synonyms: ICAM-2

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity