Stefin B (CSTB) Mouse Monoclonal Antibody [Clone ID: M2-F1]

CAT#: AM31774PU-N

Stefin B (CSTB) mouse monoclonal antibody, clone M2-F1, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name M2-F1
Applications ELISA, IF, IHC, WB
Recommended Dilution ELISA.
Immunofluorescence: 10 µg/ml.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1/500 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen CSTB antibody was raised against cSTB (AAH03370.1, 1 a.a. ~ 98 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity This antibody reacts to CSTB / Stefin B.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Storage Store the antibody at -20°C to -80°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens cystatin B (CSTB)
Background This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Defects in CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) [MIM:254800]. EPM1 is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
Synonyms Stefin-B, CPI-B, CSTB, CST6, STFB
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.