Factor VII (F7) (+VIIa) Mouse Monoclonal Antibody [Clone ID: AA-3]

CAT#: AM31847BT-N

Factor VII (F7) (+VIIa) mouse monoclonal antibody, clone AA-3, Biotin

Specifications

Product Data

• Clone Name: AA-3
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human Factor VII (AA-3) purified from plasma.
• Specificity: This antibody is specific for factor VII/VIIa (AA-3).
• Formulation: PBS
  Label: Biotin
  State: Liquid purified IgG fraction
  Stabilizer: EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens coagulation factor VII (F7), transcript variant 1
• Database Link:
  Entrez Gene 2155 Human
• Background: Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.
• Synonyms: Proconvertin, SPCA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades