Cd27 Hamster Monoclonal Antibody [Clone ID: LG.3A10]
Other products for "Cd27"
Specifications
Product Data | |
Clone Name | LG.3A10 |
Applications | FC, FN, IHC |
Recommended Dilution | ELISA: In combination with LG.8A6, it is possible to develop a double determinant ELISA to detect soluble Mouse CD27. Flow Cytometry: Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This clone (LG.3A10) has been reported to work on Paraffin tissue sections. |
Reactivities | Mouse |
Host | Hamster |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen. Fusion Partner: SP2/0 Murine Myeloma Partner. |
Specificity | Recognizes Mouse CD27 receptor. |
Formulation | PBS containing 0.02% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction from Ascites |
Concentration | 1.0 mg/ml |
Purification | Protein G Chromatography |
Gene Name | Mus musculus CD27 antigen (Cd27), transcript variant 1 |
Database Link | |
Background | CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both and T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events. |
Synonyms | TNFRSF7, CD27L receptor, T14 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.