Havcr2 Rat Monoclonal Antibody [Clone ID: 25F.1D6]

CAT#: AM31885FC-N

Havcr2 rat monoclonal antibody, clone 25F.1D6, FITC

Specifications

Product Data

• Clone Name: 25F.1D6
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry.
  Flow Cytometry.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3.
• Formulation: PBS containing 0.02% sodium azide (NaN39 as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
  Label: FITC
  State: Liquid purified IgG fraction
  Label: Fluorescein isothiocyanate isomer 1
• Concentration: 0.1 mg/ml
• Conjugation: FITC
• Gene Name: Mus musculus hepatitis A virus cellular receptor 2 (Havcr2)
• Database Link:
  Entrez Gene 171285 Mouse
• Background: This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.
• Synonyms: TIMD-3, TIM3, TIM-3, T-cell membrane protein 3, HAVCR-2