Havcr2 Rat Monoclonal Antibody [Clone ID: 25F.1D6]
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Specifications
Product Data | |
Clone Name | 25F.1D6 |
Applications | FC, IHC |
Recommended Dilution | Immunohistochemistry. Flow Cytometry. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Specificity | Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3. |
Formulation | PBS containing 0.02% sodium azide (NaN39 as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL. Label: FITC State: Liquid purified IgG fraction Label: Fluorescein isothiocyanate isomer 1 |
Concentration | 0.1 mg/ml |
Conjugation | FITC |
Gene Name | Mus musculus hepatitis A virus cellular receptor 2 (Havcr2) |
Database Link | |
Background | This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance. |
Synonyms | TIMD-3, TIM3, TIM-3, T-cell membrane protein 3, HAVCR-2 |
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