CCN3 (NOV) Mouse Monoclonal Antibody [Clone ID: 2G8]

CAT#: AM31946PU-N

CCN3 (NOV) mouse monoclonal antibody, clone 2G8, Purified

Product Images

Western Blot analysis of NOV expression in transfected 293T cell line by NOV monoclonal antibody, clone 2G8.

• 

  Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Immunoprecipitation of NOV transfected lysate using anti-NOV monoclonal antibody and Protein A magnetic bead, immunoblotted with NOV Rabbit Polyclonal antibody.

Specifications

Product Data

• Clone Name: 2G8
• Applications: ELISA, IHC, IP, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Immunoprecipitation.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant protein
• Specificity: This antibody recognizes Human NOV / CCN3.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens nephroblastoma overexpressed (NOV)
• Database Link:
  Entrez Gene 4856 Human
• Background: CCN3 is a cysteine-rich protein that is overexpressed in avian nephroblastomas. It is a member of the CCN family of proteins that includes CTGF. These proteins are encoded by a group of genes known as immediate-early genes, so named because they are expressed after induction by growth factors or certain oncogenes. The proteins share several common structural motifs: a consensus sequence present in IGF (insulin-like growth factor)-binding proteins (the IGFBP motif), an oligomeric complex-forming domain first identified in von Willebrand factor, a binding domain to soluble and matrix molecules and a dimerization (CT) domain. All CCN family members are thought to be involved in the control of cell proliferation.
• Synonyms: CCN3, IGFBP9, NOVH, NovH

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Secreted Protein