CCN3 (NOV) Mouse Monoclonal Antibody [Clone ID: 2G8]
Other products for "NOV"
Specifications
Product Data | |
Clone Name | 2G8 |
Applications | ELISA, IHC, IP, WB |
Recommended Dilution | ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Immunoprecipitation. Western Blot. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant protein |
Specificity | This antibody recognizes Human NOV / CCN3. |
Formulation | PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A Chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens nephroblastoma overexpressed (NOV) |
Database Link | |
Background | CCN3 is a cysteine-rich protein that is overexpressed in avian nephroblastomas. It is a member of the CCN family of proteins that includes CTGF. These proteins are encoded by a group of genes known as immediate-early genes, so named because they are expressed after induction by growth factors or certain oncogenes. The proteins share several common structural motifs: a consensus sequence present in IGF (insulin-like growth factor)-binding proteins (the IGFBP motif), an oligomeric complex-forming domain first identified in von Willebrand factor, a binding domain to soluble and matrix molecules and a dimerization (CT) domain. All CCN family members are thought to be involved in the control of cell proliferation. |
Synonyms | CCN3, IGFBP9, NOVH, NovH |
Reference Data | |
Protein Families | ES Cell Differentiation/IPS, Secreted Protein |
Documents
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