DNA (double stranded) Mouse Monoclonal Antibody [Clone ID: AE-2]

CAT#: AM32172PU-N

DNA (double stranded) mouse monoclonal antibody, clone AE-2, Purified

Specifications

Product Data

• Clone Name: AE-2
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections: Use paraformaldehyde fixed or frozen tissue or cell preparations.
  Recommended Positive Control: Tonsil.
  Immunohistochemistry on Formalin Fixed, Paraffin-Embedded Tissue Sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: A BALB/c mouse was immunized with nuclei of Raji Burkitt’s lymphoma cells.
  The isolated splenocytes were fused with mouse myeloma cells.
• Specificity: This Monoclonal antibody AE-2 recognizes Double Stranded DNA expressed in the nucleus of Human cells.
  AE-2 produces a homogeneous staining pattern in the nucleus of normal and malignant cells.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Background: Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
• Synonyms: Deoxyribonucleic Acid