Cd40lg Hamster Monoclonal Antibody [Clone ID: MAB0712]

CAT#: AM33407PU-N

Cd40lg hamster monoclonal antibody, clone MAB0712, Purified

Product Images

Formalin fixed and paraffin embedded mouse spleen tissue section was subjected to IHC staining of CD40 Ligand using (Left panel Red Pulp, Right panel: White Pulp).

• 

  Formalin fixed and paraffin embedded mouse tumor section was subjected to IHC staining of CD40 Ligand using (Left panel: x 20; Right panel: x 40).

Specifications

Product Data

• Clone Name: MAB0712
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometry: 1/100-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/300.
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Mouse Th1 cells.
• Specificity: This antibody detects Mouse CD40 Ligand.
  Other species not tested.
• Formulation: PBS
  State: Purified
  State: Lyophilized purified IgG fraction from Culture Supernatant
  Stabilizer: None
• Reconstitution Method: Restore with 0.4 ml sterile PBS and the final concentration is 0.5 mg/ml.
• Purification: Affinity Chromatography on Protein G
• Gene Name: CD40 ligand
• Database Link:
  Entrez Gene 21947 Mouse
• Background: CD40 ligand (CD40L), also known as CD154, TNFSF5, TRAP or gp39, is a 260 amino acid type II transmembrane glycoprotein belonging to the TNF family. Murine CD40L consists of a 22 aa cytoplasmic domain, a 24 aa transmembrane domain, and 214 aa extracellular domain bearing a single glycosylation site. CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, including NK cells, mast cells, basophils and eosinophils. Murine CD40L shares 78% amino acid sequence identity with human CD40L. Native bioactive soluble CD40L exists. Soluble human trimeric CD40L secreted by stimulated T cells has been shown to be generated by proteolysis in the microsomes. Both membrane bound and soluble CD40L induce similar effects on B cells.
• Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39