STAT1 Mouse Monoclonal Antibody [Clone ID: AT1F4]

CAT#: AM50035PU-N

STAT1 mouse monoclonal antibody, clone AT1F4, Purified

Product Images

The HepG2 cell lysate (50ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human STAT1 antibody (1:500, 1:1000, 1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detecti

Specifications

Product Data

• Clone Name: AT1F4
• Applications: ELISA, WB
• Recommended Dilution: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:1000 Recommended starting dilution is 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human STAT1 (1-712aa) purified from E. coli
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: 1.0 mg/ml
• Purification: Protein-A affinity chromatography
• Gene Name: Homo sapiens signal transducer and activator of transcription 1 (STAT1), transcript variant alpha
• Database Link:
  Entrez Gene 6772 Human
• Background: STAT1, also known as STAT91, is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway