PSME1 Mouse Monoclonal Antibody [Clone ID: AT12H3]
Other products for "PSME1"
Specifications
Product Data | |
Clone Name | AT12H3 |
Applications | ELISA, WB |
Recommended Dilution | The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant human PSME1 (1-249aa) purified from E. coli. |
Formulation | Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction |
Concentration | 1.0 mg/ml |
Purification | Protein-A affinity chromatography |
Gene Name | Homo sapiens proteasome activator subunit 1 (PSME1), transcript variant 1 |
Database Link | |
Background | PSME1, also known as PA28 alpha, is an interferon gamma (IFNG) inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an altertive proteasome activator that does not employ the use of ubiquitin. The PSME1 complex is composed of two homologous subunits, alpha and beta, which have similar catalytic properties and associate to form a hexameric ring. |
Synonyms | PSME-1, IFI5111, Proteasome activator complex subunit 1, Proteasome activator 28 subunit alpha, PA28alpha, PA28a, 11S regulator complex subunit alpha, REG-alpha, IGUP I-5111 |
Reference Data | |
Protein Pathways | Antigen processing and presentation, Proteasome |
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