CAPNS1 Mouse Monoclonal Antibody [Clone ID: AT1D11]
Other products for "CAPNS1"
Specifications
Product Data | |
Clone Name | AT1D11 |
Applications | ELISA, FC, IF, WB |
Recommended Dilution | The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant human CAPNS1 (84-268aa) purified from E. coli. |
Formulation | Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction |
Concentration | 1.0 mg/ml |
Purification | Protein-A affinity chromatography |
Gene Name | Homo sapiens calpain small subunit 1 (CAPNS1), transcript variant 1 |
Database Link | |
Background | CAPNS1, also known as Calpain small subunit 1, are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Two transcript variants encoding the same protein have been identified for this gene. |
Synonyms | Calpain small subunit 1, CSS1, CAPN4, CAPNS |
Reference Data | |
Protein Families | Druggable Genome, Protease |
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