COPZ1 Rabbit Polyclonal Antibody

CAT#: AP01468PU-N

COPZ1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of COP ?1 antibody (Cat.-No.: AP01468PU-N) in extracts from Jurkat cells.

• 

  Immunohistochemistry (IHC) analyzes of COP ?1 antibody (Cat.-No.: AP01468PU-N) in paraffin-embedded human cervix carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: COP ζ1 antibody detects endogenous levels of COP ζ1 protein. (region surrounding Ile48)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Predicted Protein Size: ~ 20 kDa
• Gene Name: Homo sapiens coatomer protein complex subunit zeta 1 (COPZ1), transcript variant 1
• Database Link:
  Entrez Gene 56447 MouseEntrez Gene 22818 Human
• Background: Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ1 subunits (also known as β-COP, γ-COP, δ-COP and ζ-1 COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, COPP and COPE subunits (also known as α-COP, COPP and ε-COP, respectively).
• Synonyms: COPZ1, COPZ, CGI-120, HSPC181, Zeta-1 COP