Calcitonin (CALCA) Sheep Polyclonal Antibody

CAT#: AP02064SU-N

Calcitonin (CALCA) sheep polyclonal antibody, Serum

Specifications

Product Data

• Applications: R
• Recommended Dilution: RIA (1/80,000).
• Reactivities: Human
• Host: Sheep
• Clonality: Polyclonal
• Immunogen: Synthetic Human Calcitonin, BSA-conjugated
• Specificity: This antibody detects Calcitonon.
  There were no cross reactivities obtained with Human Katacalcin and Human Calcitonin Gene related Peptide.
• Formulation: State: Serum
  State: Lyophilized Serum
• Reconstitution Method: Restore in aqua bidest to initial volume.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Database Link:
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
• Synonyms: CALCA, CALC1
• Note: LocusID 796