Comp Chicken Polyclonal Antibody

CAT#: AP02285PU-S

Comp chicken polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot.
• Reactivities: Rat
• Host: Chicken
• Clonality: Polyclonal
• Immunogen: Recombinant rat COMP (Fragment T3+TC)
• Specificity: This antibody detects COMP.
• Formulation: PBS pH 7,4
  State: Purified
  State: Lyophilized purified Ig fraction
• Reconstitution Method: Restore in aqua bidest.
• Database Link:
  Entrez Gene 25304 Rat
• Background: COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
• Synonyms: Cartilage oligomeric matrix protein
• Note: LocusID 25304