BCL2 Sheep Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IP, WB |
Recommended Dilution | Western Blot: 1:5,000. Immunoprecipitation. Immunofluorescence: 1:5000. |
Reactivities | Canine, Human, Rat |
Host | Sheep |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Full length recombinant bcl-2 protein |
Specificity | This antibody reacts to bcl-2. |
Formulation | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered) |
Concentration | lot specific |
Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter. |
Synonyms | BCL2, Bcl-2 alpha |
Reference Data |
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