TGFBR2 (77-148) Sheep Polyclonal Antibody

CAT#: AP05025PU-N

TGFBR2 (77-148) sheep polyclonal antibody, Purified

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Western Blot: 1:100.
  Immunohistology.
• Reactivities: Chicken
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Specificity: This antibody reacts to TGF Type II Receptor a.a. 77 - 148.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig (0.2µm sterile filtered)
• Concentration: Lot specific
• Gene Name: transforming growth factor, beta receptor II (70/80kDa)
• Database Link:
  Entrez Gene 396399 Chicken
• Background: The immunogen used was a GST fusion protein containing chick transforming growth factor b type II receptor a.a.77-148. Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor b (TGFb) is one of a number of factors that mediates this transformation. Antibodies directed against TGFb Type II recepttor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
• Synonyms: TGF-beta receptor type-2, TGF-beta receptor type II, TGF-beta type II receptor, TbetaR-II, TGFR-2