PPP2R1A Sheep Polyclonal Antibody

CAT#: AP05040PU-N

PPP2R1A sheep polyclonal antibody, Purified


USD 360.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western Blot: 1-5 µg.
Immunocytochemistry: 1/500-1/1000.
Immunoprecipitation often used in combination with Ig purified anti pp2A/C to immunoprecipitate heterotrimeric pp2A.
Reactivities Bovine, Human, Mouse, Rat
Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen A peptide conjugated to KLH corresponding to amino acids 7-19 sequence (N-terminal) of PP2A/A regulatory subunit having a MW of 65kD
Specificity This antibody recognizes Serine/Threonine Protein Phosphatase 2A/A.
Formulation PBS pH 7.4 and 0.08% Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens protein phosphatase 2 regulatory subunit A, alpha (PPP2R1A), transcript variant 1
Background Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha (PPP2R1A) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.
Synonyms Protein phosphatase 2A, PP2A subunit A PR65-alpha isoform, PP2A subunit A R1-alpha isoform
Note Predicted Molecular Weight: 65 kDa
Reference Data
Protein Families Druggable Genome, Phosphatase, Transcription Factors
Protein Pathways Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

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