PPP2R1A Sheep Polyclonal Antibody
Other products for "PPP2R1A"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Western Blot: 1-5 µg. Immunocytochemistry: 1/500-1/1000. Immunoprecipitation often used in combination with Ig purified anti pp2A/C to immunoprecipitate heterotrimeric pp2A. |
Reactivities | Bovine, Human, Mouse, Rat |
Host | Sheep |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A peptide conjugated to KLH corresponding to amino acids 7-19 sequence (N-terminal) of PP2A/A regulatory subunit having a MW of 65kD |
Specificity | This antibody recognizes Serine/Threonine Protein Phosphatase 2A/A. |
Formulation | PBS pH 7.4 and 0.08% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens protein phosphatase 2 regulatory subunit A, alpha (PPP2R1A), transcript variant 1 |
Database Link | |
Background | Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha (PPP2R1A) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit. |
Synonyms | Protein phosphatase 2A, PP2A subunit A PR65-alpha isoform, PP2A subunit A R1-alpha isoform |
Note | Predicted Molecular Weight: 65 kDa |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
Protein Pathways | Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway |
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