SH3BP2 Sheep Polyclonal Antibody

CAT#: AP05082PU-N

SH3BP2 sheep polyclonal antibody, Purified


USD 360.00

5 Days*

Size
    • 250 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western Blot: Detects a 85 kDa band in murine fibroblasts transfected with 3BP2.
Reactivities Mouse
Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
Specificity This antibody reacts to 3BP2.
Formulation Phosphate buffered saline and 0.08% sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Storage The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2
Background 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level.
Synonyms SH3 domain-binding protein 2, SH3BP-2, 3BP2, 3BP-2
Reference Data
Protein Families Druggable Genome
Protein Pathways Natural killer cell mediated cytotoxicity

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.