SLC9A6 Rabbit Polyclonal Antibody

CAT#: AP05295SU-N

SLC9A6 rabbit polyclonal antibody, Purified

Product Images

Western blot using NHE6 antibody on human brain lysate (15 ug/lane). Antibody used at 10 ug/ml. Secondary antibody, mouse anti-rabbit, used at 1:150K dilution.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot (1-5 µg/ml).
  Positive Control: Ubiquitous, most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from Human NHE6 protein
• Specificity: This antibody detects Sodium-Hydrogen Exchanger 6 (NHE6), most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
• Formulation: Phosphate buffered saline with 0.08% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Gene Name: Homo sapiens solute carrier family 9 member A6 (SLC9A6), transcript variant 1
• Database Link:
  Entrez Gene 10479 Human
• Background: Electroneutral exchange of protons for Na(+) and K(+) across the mitochondrial inner membrane. Contributes to organellar volume and calcium homeostasis.
  SLC9A6 is a monovalent sodium-selective sodium/hydrogen exchanger (NHE) that is found in the membranes of intracellular organelles such as mitochondria and endosomes. NHEs participate in a wide array of essential cellular processes, including control of intracellular pH, maintenance of cellular volume, and reabsorption of sodium across renal, intestinal, and other epithelia.
• Synonyms: NHE-6, Sodium/hydrogen exchanger 6, KIAA0267
• Note: Predicted Molecular Weight: 74 kDa

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cardiac muscle contraction