SRD5A2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP05512PU-N

SRD5A2 (C-term) rabbit polyclonal antibody, Purified


USD 530.00

5 Days*

Size
    • 50 ul

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Specifications

Product Data
Recommended Dilution Immunohistochemistry on Paraffin Sections (Heat induced epitope retrieval is required).
Positive Control: Rat Prostate.
Reactivities Human, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a C-terminal portion of native Rat 5-Alpha Reductase type 2 conjugated to Human Thyroglobulin.
Specificity This antibody is specific for 5-Alpha Rreductase type 2 and does not react with 5-Alpha Reductase type 1.
Formulation Ammonium Bicarbonate
State: Purified
State: Lyophilized purified Ig fraction
Stabilizer: None
Preservative: None
Reconstitution Method Restore in 50 µl of sterile distilled water.
Addition of Sodium Azide is recommended for long term storage.
Purification Ammonium Sulphate Precipitation
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens steroid 5 alpha-reductase 2 (SRD5A2)
Background SRD5A2 (Steroid-5-alpha-reductase, alpha polypeptide 2) is a microsomal protein. It converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Synonyms SRD5A2, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, EC=1.3.99.5, Steroid 5-alpha-reductase 2, 5 alpha-SR2, Type II 5-alpha reductase, SR type 2
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Androgen and estrogen metabolism, Prostate cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.