IL32 Rabbit Polyclonal Antibody

CAT#: AP05618PU-N

IL32 rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of whole cell lysate from Jurkat human T cell leukemia cells probed with Rabbit anti Human Interleukin-32 at 2.5 (A) and 5 (B) ug/ml

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 5 - 10 µg/ml; detects a band/s of approximately 26kDa in jurkat cell lysate.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A 16 amino acid peptide located near the centre of human IL-32.
• Specificity: This antibody recognises IL-32.
• Formulation: Phosphate buffered saline containing 0.02% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Gene Name: Homo sapiens interleukin 32 (IL32), transcript variant 1
• Database Link:
  Entrez Gene 9235 Human
• Background: IL-32 is a 26 kDa cytokine, thought to play a role in innate and adaptive immune responses. IL-32 is produced by mitogen-activated lymphocytes, interferon-gamma activated epithelial cells and IL-12, IL-18, IL-32-activated NK cells. It is expressed at elevated levels after the activation of T-cells by mitogens or the activation of NK cells by IL-2. IL-32 activates NF-kappa-B and p38 MAPK cytokine signal pathways. TNF-alpha, IL-1beta, IL-6 and 2 C-X-C chemokine family members, all involved in autoimmune and inflammatory diseases, including rheumatoid arthritis are induced by IL-32.
• Synonyms: IL-32, NK4, TAIF

Reference Data

• Protein Families: Secreted Protein