IL-1B Rabbit Polyclonal Antibody

CAT#: AP05799SU-N

IL-1B rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ELISA, FN, WB
• Recommended Dilution: ELISA: 1/500.
  Western blot.
  Functional assay: Neutralises the bioactivity of IL-1 beta. Removal of Sodium Azide is recommended prior to use.
• Reactivities: Sheep
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant IL-1 beta
• Specificity: This antibody recognizes Interleukin-1 beta (IL-1 beta).
  No cross-reactivity is seen with ovine IL-6, IL-8, MCP-1 or TNF alpha.
• Formulation: 0.09% Sodium Azide
  State: Serum
  State: Liquid serum
• Background: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
• Synonyms: IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin