p53 (TP53) pSer392 Rabbit Polyclonal Antibody

CAT#: AP05899PU-N

p53 (TP53) pSer392 rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1:1000; recognises a band of approximately 53kD in rat brain nuclear fraction lysates.
• Reactivities: Human, Monkey, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within p53 which includes phosphorylated Ser392.
• Specificity: This antibody is specific for p53, when phosphorylated at serine 392.
• Formulation: 10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
  State: Purified
  State: Liquid purified Ig
• Purification: Affinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tumor protein p53 (TP53), transcript variant 1
• Database Link:
  Entrez Gene 24842 RatEntrez Gene 716170 MonkeyEntrez Gene 7157 Human
• Background: The tumour suppressor protein p53, is expressed ubiquitously and plays an important role in blocking proliferation of damaged cells. Phosphorylation of p53 at serine 392 is reported in response to diverse stresses, for example UV irradiation.
• Synonyms: Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53, NY-CO-13

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway