Dnm1 pSer778 Sheep Polyclonal Antibody

CAT#: AP05900PU-N

Dnm1 pSer778 sheep polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1:1000; detects a band of approximately 95kDa in rat hippocampus lysates.
• Reactivities: Bovine, Canine, Chicken, Human, Mouse, Rat
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser778.
• Specificity: This antibody is specific for Dynamin when phosphorylated at serine 778.
• Formulation: 10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
  State: Purified
  State: Liquid purified Ig
• Purification: Affinity chromatography
• Database Link:
  Entrez Gene 140694 Rat
• Background: Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.
• Synonyms: DNM1, DNM