alpha 2 Macroglobulin (A2M) Goat Polyclonal Antibody
Specifications
Product Data | |
Applications | ELISA, IHC, IP, WB |
Recommended Dilution | ELISA: 1/80000 - 1/400000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Immunoprecipitation. Western Blot: 1/2000 - 1/20000. |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A2-Macroglobulin from Human Plasma. |
Formulation | 0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH 7.2 State: Purified State: Liquid purified IgG fraction Preservative: 0.01% (w/v) Sodium Azide |
Concentration | lot specific |
Purification | IgG fractionation |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. |
Synonyms | Alpha-2-M, CPAMD5, Alpha 2 macroglobulin |
Reference Data |
Documents
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in shipping.