CNTF Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Specificity | This antibody is specific to Ciliary Neurotrophic Factor (CNTF). |
Formulation | PBS, pH 7.4 containing 0.08% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | 1 mg/ml |
Purification | Affinity Chromatography on Protein A. |
Conjugation | Biotin |
Database Link | |
Background | Ciliary neurotrophic factor (CNTF) is expressed in glial cells within the central and peripheral nervous systems. CNTF stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types such as sensory, sympathetic, ciliary and motor neurons. CNTF itself lacks a classical signal peptide sequence of a secreted protein, but is thought to convey its cytoprotective effects after release from adult glial cells by some mechanism induced by injury. In addition to its neuronal actions, CNTF also acts on non neuronal cells such as glia, hepatocytes, skeletal muscle, embryonic stem cells and bone marrow stromal cells. |
Synonyms | Ciliary Neurotrophic Factor |
Reference Data |
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